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Aphexine O 200mg/200mg Tablet

Ajanta Pharma Ltd

Information updated 11 January 2026

Cefixime (200mg) Ofloxacin (200mg)110.40

Aphexine O 200mg/200mg Tablet Patient Guide

Overview Aphexine O 200mg/200mg Tablet is a combination antibiotic medication manufactured by Ajanta Pharma Ltd. It contains two active ingredients: Cefixime (200mg) and Ofloxacin (200mg). This medication is used to treat various infections and is available by prescription only.

Uses Aphexine O 200mg/200mg Tablet is indicated for the treatment of bacterial infections, including:

  • Respiratory tract infections (e.g., bronchitis, pneumonia)
  • Urinary tract infections (e.g., pyelonephritis, cystitis)
  • Skin and soft tissue infections (e.g., cellulitis, abscesses)
  • Infections of the ear, nose, and throat

Mechanism of Action Cefixime, a cephalosporin antibiotic, works by inhibiting the growth of bacteria by interfering with their cell wall formation. Ofloxacin, a fluoroquinolone antibiotic, works by inhibiting the bacterial DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication and transcription.

Dosage The recommended dosage of Aphexine O 200mg/200mg Tablet is as follows:

  • Adult patients: 1 tablet twice daily for 7-10 days
  • Pediatric patients (12-18 years): 1 tablet twice daily for 7-10 days
  • Pediatric patients (6-12 years): 1/2 tablet twice daily for 7-10 days
  • Pediatric patients (less than 6 years): Consult a doctor for dosage instructions

Side Effects Common side effects of Aphexine O 200mg/200mg Tablet include:

  • Nausea and vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Dizziness
  • Fatigue
  • Rash

Serious side effects can occur, including:

  • Allergic reactions (e.g., anaphylaxis, angioedema)
  • Liver damage
  • Kidney damage
  • Heart rhythm disturbances

Precautions Before taking Aphexine O 200mg/200mg Tablet, inform your doctor if you have:

  • A history of kidney or liver disease
  • A history of seizures or convulsions
  • A history of allergic reactions to other antibiotics
  • Any medical conditions that may interact with the medication (e.g., heart problems, muscle weakness)

FAQs

Q: What are the potential interactions between Aphexine O 200mg/200mg Tablet and other medications? A: Aphexine O 200mg/200mg Tablet may interact with other medications, such as warfarin, theophylline, and caffeine. Inform your doctor about all medications you are taking.

Q: Can I take Aphexine O 200mg/200mg Tablet if I am pregnant or breastfeeding? A: Aphexine O 200mg/200mg Tablet should be used with caution in pregnant or breastfeeding women. Consult your doctor before taking the medication.

Q: How should I store Aphexine O 200mg/200mg Tablet? A: Store Aphexine O 200mg/200mg Tablet at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Do not store the medication in the bathroom or near a heat source.

Uses

  • General Health

Side Effects

  • Consult Doctor

Have questions about Aphexine O 200mg/200mg Tablet?

Talk to a verified specialist who can guide you on dosage, alternatives, and interactions.

Safety Advice

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pregnancy

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alcohol

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driving

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