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Twinrix Adult Injection

Glaxo SmithKline Pharmaceuticals Ltd

Information updated 24 June 2026

Freeze-dried Live Attenuated Hepatitis A Vaccine (720IU) Hepatitis B Vaccine (rDNA) (20mg)1644.00

Twinrix Adult Injection Patient Guide

Overview

As a patient, it's essential to understand the purpose and benefits of the Twinrix Adult Injection. This vaccine is designed to protect you against two serious viral infections: Hepatitis A and Hepatitis B. Our goal is to provide you with clear information to help you make informed decisions about your health.

Uses

The Twinrix Adult Injection is used to:

  • Prevent Hepatitis A infection, a highly contagious liver disease that can cause symptoms such as fever, fatigue, and jaundice.
  • Prevent Hepatitis B infection, a viral disease that can cause liver damage, liver cancer, and even death.

Mechanism of Action

The Twinrix Adult Injection contains two active ingredients:

  • Hepatitis A vaccine: This vaccine uses a weakened form of the Hepatitis A virus to stimulate your immune system to produce antibodies that can fight the virus.
  • Hepatitis B vaccine: This vaccine uses a genetically engineered version of the Hepatitis B virus to stimulate your immune system to produce antibodies that can fight the virus.

When you receive the Twinrix Adult Injection, your body will recognize the weakened or genetically engineered viruses as foreign and will produce antibodies to fight them. These antibodies will help protect you against future infections.

Dosage

The recommended dosage for the Twinrix Adult Injection is:

  • A series of 3 injections, given at 0, 1, and 6 months.
  • Each injection should be given in the upper arm, just above the tricep muscle.

Side Effects

As with any vaccine, the Twinrix Adult Injection can cause side effects, which are usually mild and temporary. Common side effects include:

  • Pain, redness, or swelling at the injection site
  • Fatigue
  • Headache
  • Fever
  • Nausea or vomiting

In rare cases, more serious side effects can occur, such as:

  • Allergic reactions (e.g., hives, itching, swelling of the face, lips, tongue, or throat)
  • Severe headache or stiff neck
  • Seizures

If you experience any of these side effects, contact your healthcare provider immediately.

Precautions

Before receiving the Twinrix Adult Injection, inform your healthcare provider if you:

  • Are allergic to any of the vaccine's ingredients
  • Have a weakened immune system (e.g., due to cancer, HIV/AIDS, or taking immunosuppressive medications)
  • Are pregnant or breastfeeding
  • Have a history of seizures or other nervous system disorders
  • Have a history of allergies or reactions to vaccines

FAQs

Q: How long does the Twinrix Adult Injection provide protection against Hepatitis A and B?

A: The Twinrix Adult Injection provides long-term protection against Hepatitis A and B. After receiving the complete series of 3 injections, you will be protected against these viruses for at least 25 years.

Q: Can I get the Twinrix Adult Injection if I've already been infected with Hepatitis A or B?

A: No, if you've already been infected with Hepatitis A or B, the Twinrix Adult Injection will not provide protection against future infections.

Q: Can I receive the Twinrix Adult Injection if I'm taking other medications?

A: Inform your healthcare provider about all medications you're taking, including prescription and over-the-counter medications, vitamins, and supplements. This will help ensure that the Twinrix Adult Injection is safe for you to receive.

Uses

  • General Health

Side Effects

  • Consult Doctor

Have questions about Twinrix Adult Injection?

Talk to a verified specialist who can guide you on dosage, alternatives, and interactions.

Safety Advice

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pregnancy

Consult Doctor

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alcohol

Caution

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driving

Caution

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