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Does Fenugreek Really Boost Testosterone? Urologist Reveals the truth!

does Fen Greek actually boost testosterone I'm Dr Rea Malik urologist and pelvic surgeon and today we're continuing our series on testosterone boosters and today we're going to talk all about fenre but before I do that I just want to remind you of our brand new free ebook called better sex better life which I've compiled for you with my top 10 tips to improve pleasure and have better sex every time make sure you check out the link in the description below to get access to that so the reason I've been talking a lot about testosterone boosters is because we know that testosterone is so important for a variety of different things including as I've mentioned before sexual function libido muscle mass mood brain health just so many different things but but what you probably don't know is that people with low testosterone have been shown to have a 40% greater likelihood of dying compared to men in observational studies who have normal levels of testosterone and those with severe late onset hypogonadism meaning energ deficiency that occurs after 40 years of age were at a five time greater risk of all cause mortality compared to men without this condition and this is even when you control for a variety of different things including age body mass index smoking and overall General Health so this is a serious condition that needs serious attention it makes sense that people are often looking for supplements they can buy over over the counter to boost their testosterone now what about fenek what is it so it's a plant it's usally found in areas like North Africa Asia southern Europe and it contains these very small golden brown seeds and it's been used for a lot of alternative medicine in Chinese medicine in fact I've personally used it for um lactation purposes because we use it often in Indian culture to help it's believed to help improve breast milk production and there's also some potential benefits for testosterone boosting and the theory is that this is probably an incomplete 5 Alpha reductase and aromatase inhibitor meaning that it's preventing the breakdown of testosterone into estral or dihydrotestosterone and the active ingredient in fenor Greek is what's called glycosides and saponins and one of the saponins that it's highing is called diosgenin and this is a precursor for progesterone and testosterone so subsequently it's thought to result in an increase in testost so let's start on the data in fact there's been a reasonable number of studies now they're not all high quality they're not all a large number of participants but there is some data on fenre so one study was a systematic review looking at a total of Six studies and they looked at either fenor Greek extract test ofen or fenu FG which is another Fen Greek extract and then the other ones looked at ind9 which is manufactured by indis biotech and furosap which was manufactured by chemical resources and then lastly they looked at grunin which was also manufactured by indis biotech so these are all sort of formulated supplements and five of the studies were randomized double blind Placebo controlled trials so randomized Placebo control trials are considered the highest level of evidence when they are created without bias and they are powered to detect a difference and so these again there can be good randomized control trials and bad randomized control trial but generally the design of the study is the most important the other six study was a double blind Placebo controlled crossover study mean they could cross over to the intervention arm so ultimately pretty design studies they looked at a total of 366 participants and the men were anywhere from age 18 to 72 years of age and each individual study had anywhere from 16 people to 120 people now of those Six studies four show an increase in serum testosterone concentrations and two showed no significant difference and we're going to get into the data into the nitty-gritty so we can go over it let's start with the largest study so the first largest study was again a double blind randomized clinical trial in 2016 which was based in Australia and they took 120 men this is the largest study 60 men were in the control group and 60 men were in the intervention group and received the fen Greek seed extract called test ofense now these guys at Baseline were overweight and obese they were an average age of 54 and their average body mass index was 30 and when you design these days you have to look at the primary outcome so the primary outcome of this study was particularly looking at the symptoms of Androgen deficiency and they measured this by looking at a validated questionnaire called the Aging male symptoms they want to see do your symptoms get better taking this medication or this supplement they also looked at other secondary outcomes like sexual function sex hormone concentrations and even sleep quality so in terms of enden deficiency symptoms they did find a significant difference between groups so in the entire score which was like overall score as well as subscores of sexual subscores as well as somatic subscores now what is a somatic subscore it looks at four questions specifically looking at General wellbeing muscle aches and Sleep Quality as well as excessive sweating and so in those groups they saw again overall they saw an improvement they also saw a difference in sexual function using another questionnaire in terms specifically of sexual arousal and sex drive they also noticed that in terms of erections they had an average of one erection per week prior to this study and then after they were supplemented they noticed that they were having about two to three erections per week in terms of hormones they saw a small but what they call significant increase in testosterone specifically the total testosterone values from the Baseline to the 12th week which was going from 12.3 nanomoles per liter to 13.8 nanomoles per liter and they also no an increase in that calculated free testosterone from 241 PES per liter to 264 picomoles per liter now they did not see any significant side effects with the supplementation however less than 5% did have headaches associated with taking the supplement so bottom line they saw that it was safe and effective at least reducing symptoms and improving sexual function and they saw this slight increase in testosterone but is it clinically significant that's a bit unclear however we have to take this data with a grain of salt because it was funded by Gen Corp Pacific Hong Kong which supplied the supplement that was used in the study now the next largest study was also done by the same group it was a hundred men in Australia who also had symptoms of BPH so benign prosthetic hyperplasia or en llarge prostate so that could be things like having a weak stream having hesitancy waiting for your stream to start um having a stop and start stream or having sort of a very weak Stream So this study was another 12we study of 300 milligram of testen twice a day so 600 milligram total and in this study they actually did not see a significant difference in total testosterone or free testosterone for that matter now other studies St that were looked at in this meta analysis were much smaller and mostly done in young healthy men who were not overweight and didn't have any other medical conditions like BPH so briefly in 2016 they did a study for eight weeks out of India looking at 60 men 30 who got the supplementation and 30 who were in the control group and they used what's called fenu FG which had 300 Mig of fenu Greek seed extract twice a day again 600 Mig daily but in this study they also had them do a resistance training program and so with both the resistance training program as well as the fenu FG they saw a really significant increase in free testosterone of about 98% and they went from 17.76% young healthy men between the ages of 18 and 30 in the United States and they looked at 40 men total 20 in the control group 20 receiving the fener Greek supplementation and they used something called furosap which was 250 mg one capsule once daily now this particular extract is enriched with those seon we talked about earlier and it had 20% of protodioscin which is a steroidal stonin and so ideally they should be even if the dose in is lower they're getting enough of the supplement to see a difference and so in this study they did see a significant increase in the serum testosterone and it went from 545 to 669 so a 23 is% increase and lastly in another 8-week study done in the US looking at 30 men and 17 in the intervention group and 13 in the control group using a different Fen Greek extract 500 mg once daily saw a significant increase in serum total testosterone by about 6% or so they also see that the bioavailable testosterone so that's free and testosterone Bound by albumin increased by about 12% so is it safe some people do report they get sort of a like a sweet body odor like a maple syrupy odor when taking it um but otherwise there are some potential side effects so more most often it is GI issues like diarrhea nausea occasionally some people will get headaches or dizziness as one of the studies mentioned now large doses of fen Greek extract can cause a significant drop in blood sugar and sometimes you can also see allergic reactions particularly if you have allergic reactions to other things like peanuts um you may be more likely to get allergic reactions to fenugreek now there have been some reports of people having fenugreek resulting in liver toxicity uh but this is very rare there's also report of a skin condition called toxic epidermal necrolysis which is again exceedingly rare but there are always risks even with supplements it's not that you take something natural and you're not at risk so if you are taking if you have a liver condition if you're taking diabetic medications blood thinners or medication called theophine or mopol fenre can interact with those medications so make sure you talk to your doctor especially if you're on a bunch of medications now I want to share this there's one published report where a young man had a new onset a case of bilateral blood clots in the lungs or pulmonary emm 3 months after starting an over-the-counter Fen Greek extract so while this is one case report it does serve to tell you that supplements are not without risk so what do I think about fener Greek well the largest studies we reviewed showed either a very small benefit or none at all now the smaller studies tended to show a pretty significant benefit so what do I think I think if you are a healthy young man man who has no other medical conditions it may benefit you however if you're overweight or you have other medical conditions you may not see the benefit of fener Greek in which case I would probably be weary of starting a supplement with potential side effects or interactions with other medications you may already be on so and if you followed me for some time you know that I talk about supplements with caution because there's no regulation in terms of the supplement industry often times these supplements are mixed with other compounds or substances that are not on the label and taking those without knowledge of what's in there can be dangerous and have really dangerous side effects so ultimately use supplements cautiously and I hope you guys found this helpful and useful next week we're going to be talking about Tribulus terrestris which is a very common testosterone boosting supplement that's often found in combination with other supplements but we're going to look at specifically the data on those individual supplements now if you missed my last video on andrastin diione andrastin dial and DHA make sure you check that one out and as always want to take care of yourself because you're worth it

Dr.

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